Bioequivalence and Bioavailability Forum

average bioequivalence: MLE vs. REML [General Statistics]

posted by Mahmoud – Jordan, 2023-03-15 09:35 (12 d 14:07 ago) – Posting: # 23503
Views: 354

❝ ❝ MLE method better when number of fixed effects ≤ 4.

❝ ❝ REML method better when number of fixed effects > 4.

❝

❝ Hi! Always use REML. Use ML only if you know exactly why.

The greater the number of fixed effects, the greater the difference between REML and ML.

average bioequivalence: MLE vs. REML Mahmoud 2023-03-11 12:21 [General Statistics]
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  - average bioequivalence: MLE vs. REMLMahmoud 2023-03-15 08:35
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