average bioequivalence: MLE vs. REML [General Sta­tis­tics]

posted by Mahmoud  – Jordan, 2023-03-15 09:35 (432 d 19:02 ago) – Posting: # 23503
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❝ ❝ MLE method better when number of fixed effects ≤ 4.

❝ ❝ REML method better when number of fixed effects > 4.


❝ Hi! Always use REML. Use ML only if you know exactly why.


The greater the number of fixed effects, the greater the difference between REML and ML.

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