Hooker, Moellenhoff et al. are moving MBBE forward [BE/BA News]

posted by mittyri  – Russia, 2023-01-11 16:32 (855 d 12:54 ago) – Posting: # 23421
Views: 8,429

Hi Helmut and all!

just want to share model based approaches FDA is working on with different scentists.
Uppsala Universitet raises the flag:
Hooker #1
Hooker #2
He claims that model averaging should help in case of troubles with model building.

Kathrin Moellenhof with colleagues (another giant there: France Mentre) are attacking classical BE approaches from other side.
Interesting results of TIE estimation. Simulation-based only.

In PubMed you can see multiple papers referencing this article.

Kind regards,
Mittyri

Complete thread:

UA Flag
Activity
 Admin contact
23,424 posts in 4,927 threads, 1,671 registered users;
143 visitors (0 registered, 143 guests [including 13 identified bots]).
Forum time: 06:26 CEST (Europe/Vienna)

A statistical analysis, properly conducted, is a delicate dissection of
uncertainties, a surgery of suppositions.    Micheal J. Moroney

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5