Questions on understanding the 4-way RSABE method SAS code [RSABE / ABEL]

posted by Helmut Homepage – Vienna, Austria, 2023-01-04 15:02 (34 d 11:01 ago) – Posting: # 23418
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Hi Winnie,

❝ I am a new learner and I am trying on understanding the 4-way RSABE method SAS code provided by FDA: […]

❝ I found some discussion about the S2wr and it is really helpful to me. About the ilat, my understanding is that the model is a simple linear model and the estimate is the least square mean.


I don’t speak SAS but isn’t it a restricted maximum likelihood estimate?

❝ My R code example is as follows: […]


I’m short in time right now; compare it to Detlew’s script in base R.

❝ My question is 1) how to interpret x and critbound=(x+y)+sqrt(((boundx-x)**2)+((boundy-y)**2))? Is there any related explanation about them?


Haha, ‘the unknown x’. :-D I’m aware of only one reference,* which is – regrettably – not in the public domain.



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