Bioequivalence and Bioavailability Forum

Observations in a linear model [General Statistics]

posted by Helmut – Vienna, Austria, 2022-11-16 10:49 (524 d 05:08 ago) – Posting: # 23369
Views: 2,361

Hi ElMaestro,

❝ If it makes a difference to have more replicates, or something along such lines, please put more word to it. It is way too vague for me.

❝

❝ Please at least define "it" and "difference" in your own context with ample words.

I try. Two examples:

Two calibration curves spanning the same range with either n single measurements or n/2 duplicates.
A 2×2×2 crossover with n subject vs a 4-period full replicate design with n/2 subjects.

The question was whether the estimates of the models (obtained by single observations or replicates) are different.

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz

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