Bioequivalence and Bioavailability Forum • Washout based on mean ± SD of t½

Washout based on mean ± SD of t½ [Design Issues]

posted by Imph – 2022-09-25 15:52 (576 d 05:51 ago) – Posting: # 23318
Views: 3,418

hello,

I want to use a pharmacokinetic data from the literature and this data is provided in the form: mean ±SD, is it correct to use only the mean without taking into account the standard deviation?
For example I want to calculate a washout duration of seven times t1/2. This t1/2 is provided in the form: mean ±SD. Is it right to do "7 x t1/2 mean" without taking into consideration the SD?.

Thank you in advance

Edit: Category and subject line changed; see also this post #1. [Helmut]

Complete thread:

Washout based on mean ± SD of t½Imph 2022-09-25 13:52
- Washout based on mean ± SD of t½ Helmut 2022-09-25 16:08
  - Washout based on mean ± SD of t½ Imph 2022-09-26 15:24
    - Washout based on mean ± SD of t½ Shuanghe 2022-09-26 17:34
    - Washout based on mean ± SD of t½ Helmut 2022-09-26 17:35
    - If you have data… Helmut 2022-09-27 11:52
      - If you have data… Imph 2022-10-25 09:21
  - Washout based on mean ± SD of t½ Imph 2023-05-26 23:31
    - Washout based on mean ± SD of t½ Helmut 2023-05-27 06:52
      - Washout based on mean ± SD of t½ Imph 2023-05-27 08:36