Inactive Glucuronide metabolite [Bioanalytics]

posted by professionalr – India, 2022-08-12 12:56 (1008 d 15:12 ago) – Posting: # 23217
Views: 2,564

Hi Narra,

❝ Could you please explain if any compound is having inactive glucuronide metabolite and it's Cmax concentration was not available in the public domain. Which concentration need to spike to check the back conversion is happens to parent compound.


Did you checked the availability of pharmacokinetic information of that inactive glucuronide metabolite in FDA Accessdata or EMA's Public Assessment Reports, usually you may get the information from the above two.
—
Thanks,
RP.

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