Drug-drug interaction with two different route of admi­nistration [Design Issues]

posted by Mr.Rao – India, 2022-07-27 10:31 (501 d 21:01 ago) – Posting: # 23182
Views: 1,441

Dear All,

from below reference link they are concluded there is no clinically relevant drug–drug interaction between CHF 5993 and result of cimetidine co-administration, with total exposure increased by 16 %, and peak concentration by 26 %.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340825/


I need to know how they concluded.

Looking forward to hear in details.


Thansk,


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! Why didn’t you ignore Ohlbe’s note? [Helmut]

Complete thread:

UA Flag
Activity
 Admin contact
22,823 posts in 4,786 threads, 1,633 registered users;
31 visitors (0 registered, 31 guests [including 7 identified bots]).
Forum time: 06:32 CET (Europe/Vienna)

In these matters the only certainty is
that nothing is certain.    Pliny the Elder

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5