Drug-drug interaction with two different route of admi­nistration [Design Issues]

posted by Mr.Rao – India, 2022-07-27 10:31 (130 d 02:43 ago) – Posting: # 23182
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Dear All,

from below reference link they are concluded there is no clinically relevant drug–drug interaction between CHF 5993 and result of cimetidine co-administration, with total exposure increased by 16 %, and peak concentration by 26 %.


I need to know how they concluded.

Looking forward to hear in details.


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! Why didn’t you ignore Ohlbe’s note? [Helmut]

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