Bioequivalence and Bioavailability Forum • Could we design the RCT as a non-inferiority trial at this situation?

Could we design the RCT as a non-inferiority trial at this situation? [Design Issues]

posted by dennis001 – Hong Kong, 2022-07-27 07:21 (1023 d 23:57 ago) – Posting: # 23181
Views: 3,854

Dear ElMaestro
Thanks!

❝ Clearly a case for an NI trial one way or another.

Thank you for your comment that helped to assuage my doubts.

❝ Clearly a case for a scientific advice where you need the authority's nod for margin and design before you kick off.

Ok. we will discuss with them.

Complete thread:

Could we design the RCT as a non-inferiority trial at this situation? dennis001 2022-07-24 17:39 [Design Issues]
- Non-Superiority Helmut 2022-07-25 16:37
  - Non-Superiority dennis001 2022-07-26 02:32
    - Non-Superiority Helmut 2022-07-26 15:04
      - Non-Superiority dennis001 2022-07-27 05:18
        
        Placebo effect Helmut 2022-07-27 12:17
- Could we design the RCT as a non-inferiority trial at this situation? ElMaestro 2022-07-26 12:44
  - Could we design the RCT as a non-inferiority trial at this situation?dennis001 2022-07-27 05:21

Admin contact
23,424 posts in 4,927 threads, 1,672 registered users;
143 visitors (0 registered, 143 guests [including 11 identified bots]).
Forum time: 07:19 CEST (Europe/Vienna)

A statistical analysis, properly conducted, is a delicate dissection of
uncertainties, a surgery of suppositions. Micheal J. Moroney

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC

Ing. Helmut Schütz