Could we design the RCT as a non-inferiority trial at this situation? [Design Issues]

posted by ElMaestro  – Denmark, 2022-07-26 12:44 (18 d 01:04 ago) – Posting: # 23178
Views: 327

Hi dennis001

» So, could we design the RCT as a non-inferiority trial?

Clearly a case for an NI trial one way or another.

» Moreover, how to defining the non-inferiority margin at the situation?

Clearly a case for a scientific advice where you need the authority's nod for margin and design before you kick off.

Pass or fail!

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