Drug-drug interaction with two different route of administration [Design Issues]

posted by Mr.Rao – India, 2022-07-21 13:24 (587 d 08:35 ago) – Posting: # 23153
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❝ I think the information provided is too little.

Dear Shah,

Information we received from sponsor:

Sponsor need to check their X-Drug for Idiopathic pulmonary fibrosis treatment along with nintedanib.

First, we will provide the nintedanib for 8 days and we will collect the PK sample and from days 9-16 we will provide both nintedanib and X-Drug and we will collect PK samples, from that sponsor need to check Drug-drug interactions.

Here X-Drug is inhaler and nintedanib is tab/cap.

So what is the procedure.


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]

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