Bioequivalence and Bioavailability Forum • Drug-drug interaction with two different route of administration

Drug-drug interaction with two different route of administration [Design Issues]

posted by Mr.Rao – India, 2022-07-21 13:24 (190 d 10:09 ago) – Posting: # 23153
Views: 783

❝ I think the information provided is too little.

Dear Shah,

Information we received from sponsor:

Sponsor need to check their X-Drug for Idiopathic pulmonary fibrosis treatment along with nintedanib.

First, we will provide the nintedanib for 8 days and we will collect the PK sample and from days 9-16 we will provide both nintedanib and X-Drug and we will collect PK samples, from that sponsor need to check Drug-drug interactions.

Here X-Drug is inhaler and nintedanib is tab/cap.

So what is the procedure.

Thanks,
Rao

Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Helmut]

Complete thread:

Drug-drug interaction with two different route of administration Mr.Rao 2022-07-13 13:51 [Design Issues]
- Drug-drug interaction with two different route of administration Mr.Rao 2022-07-14 09:05
  - Drug-drug interaction with two different route of administration dshah 2022-07-20 10:27
    - Drug-drug interaction with two different route of administrationMr.Rao 2022-07-21 11:24
      - Drug-drug interaction with two different route of administration dshah 2022-07-21 18:51
        
        Drug-drug interaction with two different route of administration Mr.Rao 2022-07-22 07:23
        
        Drug-drug interaction with two different route of administration Mr.Rao 2022-07-27 08:31
        
        Interpreting results of a DDI study Helmut 2022-07-27 09:52