Drug-drug interaction with two different route of administration [Design Issues]

posted by Mr.Rao – India, 2022-07-21 11:24 (23 d 02:52 ago) – Posting: # 23153
Views: 274

» I think the information provided is too little.

Dear Shah,

Information we received from sponsor:

Sponsor need to check their X-Drug for Idiopathic pulmonary fibrosis treatment along with nintedanib.

First, we will provide the nintedanib for 8 days and we will collect the PK sample and from days 9-16 we will provide both nintedanib and X-Drug and we will collect PK samples, from that sponsor need to check Drug-drug interactions.

Here X-Drug is inhaler and nintedanib is tab/cap.

So what is the procedure.


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]

Complete thread:

UA Flag
 Admin contact
22,301 posts in 4,667 threads, 1,585 registered users;
online 6 (0 registered, 6 guests [including 5 identified bots]).
Forum time: Saturday 14:17 CEST (Europe/Vienna)

In the field of observation,
chance favors only the mind that is prepared.    Louis Pasteur

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz