T1E after 1st stage in Power2Stage [Two-Stage / GS Designs]

posted by ElMaestro  – Denmark, 2022-06-24 18:25 (49 d 20:09 ago) – Posting: # 23082
Views: 785

Hi Mittyri,

» could you please guide me regarding the function to be used for T1E estimation after 1st stage of Potvin methods (Power2Stage R package)?

That would be a misnomer, I think. The T1E is a property of the testing approach. There is an alpha at stage 1 and there is an alpha at stage 2 but there is no T1E at stage 1 (or 2). There is just a well-defined T1E for the approach.
Mixing up the terms alpha and T1E is a real danger for 2-stage approaches, since in "normal" trials they are one and the same.

Pass or fail!
ElMaestro

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