Bioequivalence and Bioavailability Forum

Hi Imph,

❝ Thank you for your valuable response.

Welcome.

❝ Is it possible to conduct an analysis of variance according to the following table without assuming equality of variances?

You could but it would be wrong. Since you must not assume equal variances and in your table the residual degrees of freedom n₁+n₂–2 are the ones of the conventional t-test.

❝ Does Welch's correction only concern the calculation of confidence intervals?

You obtain also the p-value of the treatment difference (which is, however, not relevant in bioequivalence).

Cross-validated (‼) example codes are given as supplementary information to the publication mentioned in my last post:

• ESM 1 ← Open Office Calc
  
• ESM 2 ←
  
• ESM 3 ← SAS

The first one should work also in Excel.

There is no excuse to use a flawed method.