Center term in Bio­equi­valence Study [Study As­sess­ment]

posted by balakotu – India, 2022-06-08 08:03 (29 d 10:46 ago) – Posting: # 23046
Views: 335

Dear All,

We have conducted a bioequivalence study with 32 subjects in multiple centres approx.15 centers. Each center has completed 1 to 3 subjects only, whether center term is required to include in the ANOVA model in such cases? If the center term is required how we can perform the statistical analysis including center term in ANOVA model and what will be the impact on study results.


Edit: Category changed; see also this post #1[Helmut]

Complete thread:

UA Flag
 Admin contact
22,192 posts in 4,651 threads, 1,574 registered users;
online 5 (1 registered, 4 guests [including 1 identified bots]).
Forum time: Thursday 18:50 CEST (Europe/Vienna)

Any sufficiently advanced technology
is indistinguishable from magic.    Arthur C. Clarke

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz