Effect group in full replicate Bioequivalence [Study Per­for­mance]

posted by mittyri – Russia, 2022-05-15 00:30 (203 d 14:49 ago) – Posting: # 22988
Views: 449

Dear Laura,

❝ The participants will be added to the groups accordingly with the administration date of the first period (even if the other periods can have a different administration date) or the groups shall be formed accordingly with the date of administration of all the periods (for each group all the administration date of the 4 periods has to be the same)?

I would use the groups with equal administration dates, so the periods are equal within the groups. It won't hurt (CIs won't significantly change) and does not raise the questions since you are following some internal logical rules (different period dates -> different groups).

Kind regards,

Complete thread:

UA Flag
 Admin contact
22,428 posts in 4,694 threads, 1,598 registered users;
21 visitors (1 registered, 20 guests [including 9 identified bots]).
Forum time: 14:19 CET (Europe/Vienna)

Operational hectic replaces
intellectual calms.    Alexander Huiskes

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz