PK parameters [PK / PD]

Dears

if the predefined PK parameters in BE study included AUC(0-t) i.e. truncated and the practical results of t1/2 was lower than planned in protocol and allowed the calculation of AUC0-t and AUC0-inf instead, is it possible to predefine this criteria in protocols (to use AUC-inf instead of AUC 0-t in such cases) or to issue protocol deviation from the stated PK parameters?