Bioequivalence and Bioavailability Forum

Hi Martin,

❝ Would you also use mean (SD), rather than median (min, max), for the descriptive stats then, given that this then becomes a continuous variable?

Yes. The jury is out for years trying to figure out whether the distribution is normal (use \(\small{\bar{x},\,s_x}\)) or lognormal (use \(\small{\bar{x}_\textrm{geo},\,CV_\textrm{geo}}\)). See this thread for the Half-Value-Duration HVD (aka Peak-Occupancy Time 50) and the Plateau-time t_75% (aka Peak-Occupancy Time 25). Like in your case both are also continuous in the time-domain.

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Answering an unasked question: For discrete variables (e.g., t_max) I would give the median / IQR – not the range. The latter is not informative (see this article).