“Spaghetti plots” [Software]

posted by Helmut Homepage – Vienna, Austria, 2022-04-07 15:23 (83 d 03:22 ago) – Posting: # 22915
Views: 643

Hi Shatha,

» » Where does the graph come from?
» I don't know, I received it by email as a separate graph. I tried to find the reference but I didn't get it.

Maybe ask the one who sent it to you for the source.

» spaghetti plots and plots of geometric means are the XY plots that are usually generated in WinNonlin, right? As I'm not familiar with the term "spaghetti plots".

“Spaghetti plots” (i.e., overlays of subjects’ time course of concentrations grouped by treatment) is parlance used by the PK community. You plot the lines and omit the data points. Few references.1,2

  1. Bonate PL. Pharmacokinetic-Pharmacodynamic Modeling and Simulation. New York: Springer; 2nd ed. 2011. p. 359.
  2. Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Appli­ca­tions. Stock­holm: Apotekar­so­ci­eteten; 5th ed. 2016. p. 335–6, p. 704.

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