Adjusting weight to reflect group differences in Model [General Sta­tis­tics]

posted by dshah  – India/United Kingdom, 2022-03-29 20:40 (730 d 06:25 ago) – Posting: # 22884
Views: 1,704

Dear Balakotu!
As per EMA- In parallel design studies, the treatment groups should be comparable in all known variables that may affect the pharmacokinetics of the active substance (e.g. age, body weight, sex, ethnic origin, smoking status, extensive/poor metabolic status). This is an essential pre-requisite to give validity to the results from such studies.
In general, it is recommended to have balanced between treatment arms.
Regards,
Divyen

Complete thread:

UA Flag
Activity
 Admin contact
22,957 posts in 4,819 threads, 1,636 registered users;
69 visitors (0 registered, 69 guests [including 8 identified bots]).
Forum time: 02:05 CET (Europe/Vienna)

With four parameters I can fit an elephant,
and with five I can make him wiggle his trunk.    John von Neumann

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5