Bioequivalence and Bioavailability Forum • Sample size and Replicated studies

Sample size and Replicated studies [Power / Sample Size]

posted by dshah – India/United Kingdom, 2022-03-23 12:30 (371 d 02:44 ago) – Posting: # 22861
Views: 1,501

Dear Bebac user!

As your ISCV is high, you are opting for partial/fully replicate design.
But why the 90% BE range is still 80.00-125.00% where you know that you can apply the HVD concept to widen the boundary?
Regards,
Divyen Shah

Complete thread:

Sample size and Replicated studies Bebac user 2022-03-23 09:38 [Power / Sample Size]
- Sample size and Replicated studiesdshah 2022-03-23 11:30
  - Output of sampleN.scABEL() Helmut 2022-03-23 12:43
    - Output of sampleN.scABEL() - expanded limits ? d_labes 2022-03-23 16:33
      - Output of sampleN.scABEL() - expanded limits ? Helmut 2022-03-23 16:45
    - Output of sampleN.scABEL() dshah 2022-03-23 18:08
      - Don’t use FARTSSIE for SABE Helmut 2022-03-23 19:42
- Sample size larger than clinical capacity Helmut 2022-03-23 11:43
- Sample size and Replicated studies Brus 2022-03-23 14:25