R2adj improvement limit [Regulatives / Guidelines]

posted by mittyri – Russia, 2022-03-22 11:31 (55 d 07:34 ago) – Posting: # 22858
Views: 401

Hi Helmut,

» The default automatic algorithm in Phoe­nix WinNonlin (and most other software I know) is starting with the last three concentrations and maximizing \(\small{R_\textrm{adj}^2}\) until the improvement by adding data is ≤0.0001.

I was always wondering: why the limit is ≤0.0001? Not simple <0? Or maybe ≤0.01?

Kind regards,
Mittyri

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