Bioequivalence and Bioavailability Forum • Linearity

Linearity [Regulatives / Guidelines]

posted by Ohlbe – France, 2022-01-24 13:16 (815 d 08:26 ago) – Posting: # 22751
Views: 2,249

Hi John,

Does your drug show linear PK ? If not: does it show more-than-proportional increase (then the highest strength would be more sensitive to show differences in BA) or less-than-proportional increase (lowest strength would be more sensitive, giving you good arguments) ?

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Regards
Ohlbe

Complete thread:

biowaiver for higher strength jag009 2022-01-24 07:48
- biowaiver for higher strength dshah 2022-01-24 11:01
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- LinearityOhlbe 2022-01-24 12:16
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- biowaiver for higher strength wienui 2022-02-01 09:12