Bioequivalence and Bioavailability Forum

Exact (Owen’s Q) [Power / Sample Size]

posted by Helmut  – Vienna, Austria, 2021-10-20 15:26 (912 d 10:10 ago) – Posting: # 22648
Views: 3,072

Hi Imph,

❝ Thank you very much for your answer.

Welcome.

❝ From where I am, I was unable to access dileti's publications. Can you please help me get them.

Check your inbox. Two points:

1. The paper contains tables for certain CVs, T/R-ratios, and target power.
   If you want something else, don’t be tempted to interpolate. Power curves are highly nonlinear and hence, interpolation is not that easy.
   
2. Although the exact formula is given, calculating the definite integrals of the bivariate noncentral t-distribution is not trivial.

Why do you want to re-invent the wheel? PowerTOST is  Open Source (licensed under GPL-3), comes at no cost, was used in numerous publications, textbooks, and even by the … 

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

• Choosing formula for sample size Imph 2021-10-20 11:03 
  • Exact (Owen’s Q) Helmut 2021-10-20 11:36
    • Exact (Owen’s Q) Imph 2021-10-20 12:53
      • Exact (Owen’s Q)Helmut 2021-10-20 13:26
        • Exact (Owen’s Q) Imph 2021-10-24 10:41
          • n iteratively from power Helmut 2021-10-24 10:54
          • aproximate n d_labes 2021-10-24 19:26
        • Exact (Owen’s Q) Willem Talloen 2022-09-01 15:48
          • PowerTOST & FDA Helmut 2022-09-01 16:31