dropouts in replicate studies [Regulatives / Guidelines]

posted by dshah  – India/United Kingdom, 2021-09-23 19:28 (245 d 18:06 ago) – Posting: # 22591
Views: 1,021

Dear Loky do:
It is always better to ask the volunteer to complete the other period. Even if they miss one period or two period, the data can be useful in following ways:
  1. For fully replicate study- Missing a test period--> Data can be useful for Swr calculation, safety evaluation and also average BE.
  2. Fully replicate study- missing a reference period--> Useful for Swt, safety and ABE
  3. Fully replicate study--> Missing a test and reference period--> useful for ABE
  4. Partial replicate study-> missing a test period--> useful for Swr
  5. Partial replicate study--> missing a reference period--> useful for ABE.

Regards,
Dshah

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