dropouts in replicate studies [Regulatives / Guidelines]

posted by dshah  – India/United Kingdom, 2021-09-23 19:28 (368 d 19:58 ago) – Posting: # 22591
Views: 1,156

Dear Loky do:
It is always better to ask the volunteer to complete the other period. Even if they miss one period or two period, the data can be useful in following ways:
  1. For fully replicate study- Missing a test period--> Data can be useful for Swr calculation, safety evaluation and also average BE.
  2. Fully replicate study- missing a reference period--> Useful for Swt, safety and ABE
  3. Fully replicate study--> Missing a test and reference period--> useful for ABE
  4. Partial replicate study-> missing a test period--> useful for Swr
  5. Partial replicate study--> missing a reference period--> useful for ABE.

Regards,
Dshah

Complete thread:

UA Flag
Activity
 Admin contact
22,391 posts in 4,685 threads, 1,594 registered users;
online 5 (0 registered, 5 guests [including 2 identified bots]).
Forum time: Tuesday 15:27 CEST (Europe/Vienna)

Statistics. A sort of elementary form of mathematics which consists of
adding things together and occasionally squaring them.    Stephen Senn

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5