partial AUC [NCA / SHAM]
In calculation of terminal partial AUC (AUC cut off t-tlast) specified as per EMA guideline for MR formulations
in such cases what is meaning of tlast?
is this last time of blood collection or its last time of dosing interval?
for example-In study blood collection is 72.00 hrs, However dosing interval of Drug is 24.00 hrs then early partial AUC will be AUC(0-12 hrs) & what would be the Terminal Partial AUC?
Thanks and Reagrds
Edit: Category changed; see also this post #1. GL linked. [Helmut]