Bioequivalence and Bioavailability Forum • HVD Pilot: 3 candidates, 1 reference

HVD Pilot: 3 candidates, 1 reference [Design Issues]

posted by lukamar – Poland, 2021-07-20 10:54 (1003 d 22:24 ago) – Posting: # 22480
Views: 2,070

Hi ElMaestro,

❝ I usually do not recommend to use a pilot for evaluation if one of a number of Test treatments is a potential match for the Ref. This is because of the uncertainity. Some weirdo published a paper about this phenomenon, I think.

Can you please elaborate about this uncertainity more? Where is it coming from? Can you reference this weirdo's paper if possibile?

Complete thread:

HVD Pilot: 3 candidates, 1 reference Shah 2021-07-16 13:40
- HVD Pilot: 3 candidates, 1 reference ElMaestro 2021-07-16 13:51
  - HVD Pilot: 3 candidates, 1 referencelukamar 2021-07-20 08:54
    - HVD Pilot: 3 candidates, 1 reference ElMaestro 2021-07-20 09:31