HVD Pilot: 3 candidates, 1 reference [Design Issues]
❝ I usually do not recommend to use a pilot for evaluation if one of a number of Test treatments is a potential match for the Ref. This is because of the uncertainity. Some weirdo published a paper about this phenomenon, I think.
Can you please elaborate about this uncertainity more? Where is it coming from? Can you reference this weirdo's paper if possibile?