Bioequivalence and Bioavailability Forum • IV Infusion/Bolus Pk normalisation

IV Infusion/Bolus Pk normalisation [Dissolution / BCS / IVIVC]

posted by msmnainar – India, 2021-06-24 21:04 (1267 d 10:21 ago) – Posting: # 22433
Views: 2,516

Hi,

Per my previous reply, you can validate through the difference in bioavailability between your P.O and iv formulation.

IV would be considered as 100% BA, hence based on the difference you can normalize the data.

—
Sundar. M

Complete thread:

IV Infusion/Bolus Pk normalisation pharm07 2021-06-22 11:09 [Dissolution / BCS / IVIVC]
- IV Infusion/Bolus Pk normalisation drgunasakaran1 2021-06-24 06:07
- IV Infusion/Bolus Pk normalisation msmnainar 2021-06-24 07:11
  - IV Infusion/Bolus Pk normalisation pharm07 2021-06-24 07:48
    - IV Infusion/Bolus Pk normalisationmsmnainar 2021-06-24 19:04
      - IV Infusion/Bolus Pk normalisation pharm07 2021-06-25 04:51