IV Infusion/Bolus Pk normalisation [Dissolution / BCS / IVIVC]

posted by msmnainar – India, 2021-06-24 21:04 (1025 d 17:09 ago) – Posting: # 22433
Views: 1,565

Hi,

Per my previous reply, you can validate through the difference in bioavailability between your P.O and iv formulation.

IV would be considered as 100% BA, hence based on the difference you can normalize the data.

Sundar. M

Complete thread:

UA Flag
Activity
 Admin contact
22,983 posts in 4,822 threads, 1,648 registered users;
38 visitors (0 registered, 38 guests [including 4 identified bots]).
Forum time: 14:14 CEST (Europe/Vienna)

Complex, statistically improbable things are by their nature
more difficult to explain than
simple, statistically probable things.    Richard Dawkins

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5