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IV Infusion/Bolus Pk normalisation [Dissolution / BCS / IVIVC]

posted by msmnainar – India, 2021-06-24 21:04 (1429 d 02:52 ago) – Posting: # 22433
Views: 3,090

Hi,

Per my previous reply, you can validate through the difference in bioavailability between your P.O and iv formulation.

IV would be considered as 100% BA, hence based on the difference you can normalize the data.

—
Sundar. M

Complete thread:

IV Infusion/Bolus Pk normalisation pharm07 2021-06-22 11:09 [Dissolution / BCS / IVIVC]
- IV Infusion/Bolus Pk normalisation drgunasakaran1 2021-06-24 06:07
- IV Infusion/Bolus Pk normalisation msmnainar 2021-06-24 07:11
  - IV Infusion/Bolus Pk normalisation pharm07 2021-06-24 07:48
    - IV Infusion/Bolus Pk normalisationmsmnainar 2021-06-24 19:04
      - IV Infusion/Bolus Pk normalisation pharm07 2021-06-25 04:51

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Pharmacokinetics may be simply defined as
what the body does to the drug,
as opposed to pharmacodynamics, which may be defined as
what the drug does to the body. Leslie Z. Benet

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