Period effects in general [Design Issues]

posted by Helmut Homepage – Vienna, Austria, 2021-06-11 15:41 (9 d 16:48 ago) – Posting: # 22410
Views: 312

Hi Relaxation and all,

» Now, lets both wait and see, whether I got it right :-D.

You did. ;-)
In simple terms: In – any – crossover period effects mean out if (and only if) the number of treatments in each period are equal because then they are affected to the same extent.
That’s one of the reasons why we design studies for balanced sequences. Due to dropouts sequences may be imbalanced, which biases the outcome. However,

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