AUC from 0 to tau at steady state [NCA / SHAM]
nice to hear from you. Hope you are healthy.
❝ Should the concentration for time point zero (for calculation of AUC from 0 to tau) be somehow related to the pre-dose concentrations
❝ or set to zero
❝ where I think setting to zero would be in-line with the principle of superposition (e.g. have a look here).
Don't understand your thinking here.
All the best