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RegisterAUC from 0 to tau at steady state [NCA / SHAM]
Dear forum members,
I just come accross a topic relating to calculation of AUC from 0 to tau at steady state and would be happy to get the froum members thoughts on this topic:
Should the concentration for time point zero (for calculation of AUC from 0 to tau) be somehow related to the pre-dose concentrations or set to zero where I think setting to zero would be in-line with the principle of superposition (e.g. have a look here).
best regards & happy to get your thoughts
martin
I just come accross a topic relating to calculation of AUC from 0 to tau at steady state and would be happy to get the froum members thoughts on this topic:
Should the concentration for time point zero (for calculation of AUC from 0 to tau) be somehow related to the pre-dose concentrations or set to zero where I think setting to zero would be in-line with the principle of superposition (e.g. have a look here).
best regards & happy to get your thoughts
martin
Complete thread:
- AUC from 0 to tau at steady statemartin 2021-06-01 14:43
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- AUC from 0 to tau at steady state d_labes 2021-06-01 20:31
- AUC from 0 to tau at steady state Helmut 2021-06-01 22:13
Ing. Helmut Schütz
