AUC from 0 to tau at steady state [NCA / SHAM]

posted by martin  – Austria, 2021-06-01 14:43 (389 d 01:33 ago) – Posting: # 22384
Views: 1,040

Dear forum members,

I just come accross a topic relating to calculation of AUC from 0 to tau at steady state and would be happy to get the froum members thoughts on this topic:

Should the concentration for time point zero (for calculation of AUC from 0 to tau) be somehow related to the pre-dose concentrations or set to zero where I think setting to zero would be in-line with the principle of superposition (e.g. have a look here).

best regards & happy to get your thoughts

martin

Complete thread:

UA Flag
Activity
 Admin contact
22,166 posts in 4,645 threads, 1,572 registered users;
online 9 (0 registered, 9 guests [including 3 identified bots]).
Forum time: Saturday 16:17 CEST (Europe/Vienna)

Absolute certainty is a privilege of uneducated minds  and fanatics.
It is, for scientific folk, an unattainable ideal.    Cassius J. Keyser

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5