AUC from 0 to tau at steady state [NCA / SHAM]

posted by martin  – Austria, 2021-06-01 16:43 (1140 d 13:01 ago) – Posting: # 22384
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Dear forum members,

I just come accross a topic relating to calculation of AUC from 0 to tau at steady state and would be happy to get the froum members thoughts on this topic:

Should the concentration for time point zero (for calculation of AUC from 0 to tau) be somehow related to the pre-dose concentrations or set to zero where I think setting to zero would be in-line with the principle of superposition (e.g. have a look here).

best regards & happy to get your thoughts

martin

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