Two-stage design ❌ RSABE [Design Issues]

posted by Achievwin – US, 2021-05-19 21:08 (1066 d 17:27 ago) – Posting: # 22356
Views: 1,721

Thanks Helmut:

My questions is two-fold -

1) is there a precedence of conducting two stage study for 4-period full replicate design? (four periods in stage 1 and stage 2)

and

2) what kind of penalty we can factor in?

Regards,

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