Two-stage design ❎ RSABE [Design Issues]

posted by Achievwin – US, 2021-05-19 19:08 (32 d 13:30 ago) – Posting: # 22356
Views: 307

Thanks Helmut:

My questions is two-fold -

1) is there a precedence of conducting two stage study for 4-period full replicate design? (four periods in stage 1 and stage 2)

and

2) what kind of penalty we can factor in?

Regards,

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