Bioequivalence and Bioavailability Forum • Two-stage design ❌ RSABE

Two-stage design ❌ RSABE [Design Issues]

posted by Achievwin – US, 2021-05-19 21:08 (1473 d 22:01 ago) – Posting: # 22356
Views: 3,204

Thanks Helmut:

My questions is two-fold -

1) is there a precedence of conducting two stage study for 4-period full replicate design? (four periods in stage 1 and stage 2)

and

2) what kind of penalty we can factor in?

Regards,

Complete thread:

Two-stage replicate design studies for RSABE Achievwin 2021-05-14 19:20 [Design Issues]
- Two-stage design ❌ RSABE Helmut 2021-05-14 20:14
  - Two-stage design ❌ RSABEAchievwin 2021-05-19 19:08
    - Two-stage design & RSABE: Forget it! Helmut 2021-05-19 20:40