OT: BW in ANCOVA [Regulatives / Guidelines]

posted by Kumarnaidu2 – India, 2021-03-05 15:56 (938 d 02:29 ago) – Posting: # 22247
Views: 2,062

Dear All,
I have one query, In PK bio-similarity study in healthy volunteer if the recommended dose is as per bodyweight (say 5mg/kg) then in this case subject with higher bodyweight will receive more total dose as compared to the subject with lower bodyweight. Will this going to impact the serum drug level? If yes then what corrections we need to apply?

Thanks in advance

Complete thread:

UA Flag
 Admin contact
22,763 posts in 4,775 threads, 1,627 registered users;
21 visitors (0 registered, 21 guests [including 5 identified bots]).
Forum time: 19:26 CEST (Europe/Vienna)

A little Learning is a dang’rous Thing;
Drink deep, or taste not the Pierian Spring:
There shallow Draughts intoxicate the Brain,
And drinking largely sobers us again.    Alexander Pope

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz