Bioequivalence and Bioavailability Forum

Hi Mikkabel,

❝ Could you please inform me if it is an issue related to the software (Winonlin) or is it related to the model used?

It is the design combined with the model, but it is not "a problem" and your data will allow an interpretation. Yes, certain things may be suboptimal and there's always an opportunity to balk at bias one way or another, but the data will surely allow analysis and interpretation.

❝ Additionally, could you explain me how to interpret these results and what should be the impact on the results obtained form the analysis?

You did not provide info on sequences, dropouts, missing periods etc. You can send me your data, specify the purpose and I will be happy to propose some degree of interpretation.