Reformulate… [Study As­sess­ment]

posted by Helmut Homepage – Vienna, Austria, 2021-02-15 11:59 (1138 d 04:33 ago) – Posting: # 22209
Views: 1,345

Hi Ibrahim,

❝ I am confusing to be sure that the test product is bad, so i am asking your help to know the real cause of these results.


Difficult to guess the ‘real cause’ but repeating the study in a larger sample size – given the point estimates – is futile. Even if you believe that the result were due to chance and hope that the point estimates will shift to 0.85 you would need hundreds of subjects to show BE with 80% power.
BTW, the CV of AUC (~0.351) is larger than the one of Cmax (~0.245). Possible but uncommon.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
Activity
 Admin contact
22,957 posts in 4,819 threads, 1,636 registered users;
116 visitors (0 registered, 116 guests [including 6 identified bots]).
Forum time: 16:32 CET (Europe/Vienna)

With four parameters I can fit an elephant,
and with five I can make him wiggle his trunk.    John von Neumann

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5