Bioequivalence and Bioavailability Forum • If we have any methods to widen CI in parallel design with high variance drug?

If we have any methods to widen CI in parallel design with high variance drug? [RSABE / ABEL]

posted by ElMaestro – Denmark, 2021-02-02 12:12 (1178 d 00:51 ago) – Posting: # 22200
Views: 1,807

Hi libaiyi,

❝ (...) So my quesion is if we have any method to widen the CI like RSABE in cross-over study?

I don't think there is any authority generally willing to widen the acceptance range in parallel trials involving humans (they'd perhaps do it if you were studying pMDI's in vitro etc).

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Pass or fail!
ElMaestro

Complete thread:

If we have any methods to widen CI in parallel design with high variance drug? libaiyi 2021-02-02 09:39
- If we have any methods to widen CI in parallel design with high variance drug?ElMaestro 2021-02-02 11:12
  - If we have any methods to widen CI in parallel design with high variance drug? libaiyi 2021-02-02 11:40