Significant effects: Don’t worry, be happy! [General Sta­tis­tics]

posted by Helmut Homepage – Vienna, Austria, 2020-12-22 17:27 (1213 d 16:26 ago) – Posting: # 22154
Views: 2,009

Hi Moloko,

❝ Could somebody help me with my doubts about significant sequence/treatment/period

❝ effects in BE study?

Search the forum for sequence effect, treatment effect, and period effect. Lots of posts, references, etc. See also the articles about carryover and a significant treatment effect.

❝ My СI-s are within the range of 80.000% - 125.000%, so formally BE acceptance criterion is met.

Excellent. Open a bottle of champagne. :party:

❝ But these p-values scare me... :confused:

❝ I don't have much experience in BE and I think it is not good then period or sequence factor influences PK-parameter.

See also here for the sequence effect and there for the treatment effect. The period effect cancels out in a crossover study anyway.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
 Admin contact
22,987 posts in 4,824 threads, 1,663 registered users;
96 visitors (0 registered, 96 guests [including 5 identified bots]).
Forum time: 10:54 CEST (Europe/Vienna)

The only way to comprehend what mathematicians mean by Infinity
is to contemplate the extent of human stupidity.    Voltaire

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz