Different sampling time points and Blinding [Bioanalytics]

posted by Helmut Homepage – Vienna, Austria, 2020-12-11 17:44 (655 d 05:12 ago) – Posting: # 22145
Views: 1,450

Hi ElMaestro,

» » Keep the number of time points equal and give the sequence of samples (1, 2, …, n) and not the time points themselves (t1, t2, …, tn) on the vials’ label.
»
» […] I guess one could pad the series holding only 20 samples with a sample 21 and 22 based on extracted un-spiked plasma. That would kind of win the olympic gold, wouldn't it?

Perhaps silver.

» The analyst will presumably be able to tell nothing about the nature of samples due to just the number of samples per series […].

Evidently, my dear Dr Watson. But: Sooner or later a smart analyst would start to wonder why in one period the last two samples are always BLQ.

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