Different sampling time points and Blinding [Bioanalytics]

posted by Helmut Homepage – Vienna, Austria, 2020-12-11 17:44 (130 d 19:06 ago) – Posting: # 22145
Views: 684

Hi ElMaestro,

» » Keep the number of time points equal and give the sequence of samples (1, 2, …, n) and not the time points themselves (t1, t2, …, tn) on the vials’ label.
»
» […] I guess one could pad the series holding only 20 samples with a sample 21 and 22 based on extracted un-spiked plasma. That would kind of win the olympic gold, wouldn't it?
Perhaps silver.

» The analyst will presumably be able to tell nothing about the nature of samples due to just the number of samples per series […].
Evidently, my dear Dr Watson. But: Sooner or later a smart analyst would start to wonder why in one period the last two samples are always BLQ.
—
Dif-tor heh smusma 🖖
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

Activity
 Admin contact
21,419 posts in 4,475 threads, 1,510 registered users;
online 13 (0 registered, 13 guests [including 3 identified bots]).
Forum time: Wednesday 13:50 CEST (Europe/Vienna)

In the Middles Ages the lingua franca of science was Latin.
Nowadays the language of science is bad English.    Anonymous

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5