Bioequivalence and Bioavailability Forum

Different sampling time points and Blinding [Bioanalytics]

posted by Helmut  – Vienna, Austria, 2020-12-11 11:38 (1230 d 18:10 ago) – Posting: # 22141
Views: 1,972

Hi Pharma_88,

❝ Analyst is always blind …

Analytics would be a tough job for a blind analyst.
You mean blinded for treatment.

❝ By keeping different sampling time points i.e. 20 time-points for test and 22 time points for reference, whether analyst will blind in this condition?

Of course, not (assuming that he/she is not stupid). Sometimes you aim at different sampling times (say when comparing MR to IR, DR to IR, IR to IV or an solution) in order to have an optimal schedule describing the profiles.
Keep the number of time points equal and give the sequence of samples (1, 2, …, n) and not the time points themselves (t₁, t₂, …, t_n) on the vials’ label.

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


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Complete thread:

• Different sampling time points and Blinding Pharma_88 2020-12-11 05:22 [Bioanalytics] 
  • Different sampling time points and BlindingHelmut 2020-12-11 10:38
    • Different sampling time points and Blinding ElMaestro 2020-12-11 11:07
      • Different sampling time points and Blinding Helmut 2020-12-11 17:44
        • Different sampling time points and Blinding ElMaestro 2020-12-11 21:57
          • Blinding… Helmut 2020-12-12 12:06