Log in
RegisterDextromethorphan [Dissolution / BCS / IVIVC]
» I read papers where it has classified as Class II, but also I found several publications that describe Dextromehorphan HBr as very high soluble substance.
I gone through reviews, I found Dextromehorphan Practically insoluble in water.
The Waiver request of in-vivo testing: 30 mg/600 mg based on acceptable bioequivalence studies on the 60 mg/1200 strength, acceptable dissolution testing across all strengths.
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Ohlbe]
I gone through reviews, I found Dextromehorphan Practically insoluble in water.
The Waiver request of in-vivo testing: 30 mg/600 mg based on acceptable bioequivalence studies on the 60 mg/1200 strength, acceptable dissolution testing across all strengths.
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Ohlbe]
Complete thread:
- Dextromethorphan begoña 2020-10-08 12:14 [Dissolution / BCS / IVIVC]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Dextromethorphan Sridhar.E 2020-10-08 12:27
- Dextromethorphan begoña 2020-10-08 12:35
- DextromethorphanSridhar.E 2020-10-08 12:59
- Dextromethorphan begoña 2020-10-08 12:35
- Dextromethorphan: Class II? Helmut 2020-10-08 12:54
- Dextromethorphan Sridhar.E 2020-10-08 12:27
Ing. Helmut Schütz