Dextromethorphan [Dissolution / BCS / IVIVC]
❝ I read papers where it has classified as Class II, but also I found several publications that describe Dextromehorphan HBr as very high soluble substance.
I gone through reviews, I found Dextromehorphan Practically insoluble in water.
The Waiver request of in-vivo testing: 30 mg/600 mg based on acceptable bioequivalence studies on the 60 mg/1200 strength, acceptable dissolution testing across all strengths.
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Ohlbe]