Dextromethorphan [Dissolution / BCS / IVIVC]
❝ Dextromethorphan hydrobromide belongs to the class II of biopharmaceutics classification system (BCS), exhibits low solubility and high permeability.
I read papers where it has classified as Class II, but also I found several publications that describe Dextromehorphan HBr as very high soluble substance.
I was wondering if I could ask for a biowaiver, during the evaluation of an oral product containig dexthrometorphan.
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Helmut]