Bioequivalence and Bioavailability Forum

Adjusted indirect comparisons: Algebra [General Statistics]

posted by d_labes – Berlin, Germany, 2020-10-01 19:03 (1704 d 17:32 ago) – Posting: # 21961
Views: 4,031

Dear Helmut,

❝ ... The error term in the 2×2×2 crossover is given by $$SE_\textrm{(d)}=SE_\Delta=\widehat{\sigma}_\textrm{w}\sqrt{\frac{1}{n_\textrm{1}}+\frac{1}{n_\textrm{2}}},\tag{2}$$where $\small{\widehat{\sigma}_\textrm{w}=SD_\textrm{w}=\sqrt{MSE}}$ from ANOVA. Alternatively we can write $$SE_\Delta=\sqrt{\frac{SD_{\textrm{w}}^{2}}{2}\left (\frac{1}{n_\textrm{1}}+\frac{1}{n_\textrm{2}}\right )}\tag{3}$$

Here I can't follow you. From where arises the 2 in formula (3)

—
Regards,

Detlew

Complete thread:

Adjusted indirect comparisons: Algebra Helmut 2020-10-01 16:41 [General Statistics]
- Adjusted indirect comparisons: Algebrad_labes 2020-10-01 17:03
  - Adjusted indirect comparisons: Typo Helmut 2020-10-01 17:13
- SE of ∆? Helmut 2020-10-02 14:56
  - SE of ∆? or what? d_labes 2020-10-02 18:54
    - SE of ∆ Helmut 2020-10-02 22:29
      - SE of ∆ d_labes 2020-10-04 10:23

Adjusted indirect comparisons: Algebra [General Sta­tis­tics]

Complete thread:

Adjusted indirect comparisons: Algebra [General Statistics]