differences in lambda_z calculation between PHX and PK package in R [Software]

posted by mittyri – Russia, 2020-09-27 18:25 (115 d 02:06 ago) – Posting: # 21943
Views: 467

Dear All,

some time ago I discovered the difference between PHX and 'PK' package in R regarding lambda_z calculation for sparse dataset analysis.
My question is which one looks more reasonable for you
- PHX gets means of concs and then logtransforms it to prepare for regression analysis
- PK gets logs and then calculates means for that logs to prepare for regression analysis

what do you think?

Kind regards,
Mittyri

Complete thread:

Activity
 Admin contact
21,308 posts in 4,444 threads, 1,489 registered users;
online 7 (1 registered, 6 guests [including 3 identified bots]).
Forum time: Wednesday 19:32 CET (Europe/Vienna)

Power: That which is wielded by the priesthood of
clinical trials, the statisticians, and a stick which they use
to beta their colleagues.    Stephen Senn

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5