Bioequivalence and Bioavailability Forum • Zero order helps often

Zero order helps often [Regulatives / Guidelines]

posted by PharmCat – Russia, 2020-09-11 02:33 (452 d 18:39 ago) – Posting: # 21917
Views: 2,316

Hi Helmut!

» In many cases a good model is similar to an infusion...

I thin it can be look like this:

[image]

For ODE system:


function pkf!(du,u,p,t)

    if u[1] > 0 px = 0.8 else px = 0 end

    du[1] = - px

    du[2] = - p[1] * u[2] + px

    du[3] =   p[1] * u[2] - p[2] * u[3]
end

u0 = [10.000, 0.000, 0.0]
p = [0.3, 0.04]

Complete thread:

EMA: Waiving MD study Helmut 2020-09-09 16:21 [Regulatives / Guidelines]
- EMA: Waiving MD study wienui 2020-09-09 17:43
  - EMA: Waiving MD study Helmut 2020-09-09 19:26
- PK model PharmCat 2020-09-10 20:12
  - Zero order helps often Helmut 2020-09-10 22:26
    - Zero order helps oftenPharmCat 2020-09-11 02:33
      - Distributed delay mittyri 2020-09-11 05:31