Assumptions in BE [Off Topic]

posted by Helmut Homepage – Vienna, Austria, 2020-08-31 15:33 (332 d 16:53 ago) – Posting: # 21903
Views: 841

Dear all,

discovered* a nice formula expressing two main assumptions in BE, namely that doses and clearances are equal.$$\frac{F_\textrm{T}}{F_\textrm{R}}=\frac{\frac{AUC_\textrm{T}\times CL_\textrm{T}}{dose_\textrm{T}}}{\frac{AUC_\textrm{R}\times CL_\textrm{R}}{dose_\textrm{R}}}=\frac{AUC_\textrm{T}\times CL_\textrm{T}}{AUC_\textrm{R}\times CL_\textrm{R}}=\frac{AUC_\textrm{T}}{AUC_\textrm{R}}$$


Dif-tor heh smusma 🖖
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

Activity
 Admin contact
21,592 posts in 4,514 threads, 1,532 registered users;
online 4 (0 registered, 4 guests [including 3 identified bots]).
Forum time: Friday 08:26 CEST (Europe/Vienna)

It is a capital mistake to theorise before one has data.    Arthur Conan Doyle

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5