Assumptions in BE [Off Topic]

posted by Helmut Homepage – Vienna, Austria, 2020-08-31 15:33 (630 d 03:26 ago) – Posting: # 21903
Views: 1,097

Dear all,

discovered* a nice formula expressing two main assumptions in BE, namely that doses and clearances are equal.$$\frac{F_\textrm{T}}{F_\textrm{R}}=\frac{\frac{AUC_\textrm{T}\times CL_\textrm{T}}{dose_\textrm{T}}}{\frac{AUC_\textrm{R}\times CL_\textrm{R}}{dose_\textrm{R}}}=\frac{AUC_\textrm{T}\times CL_\textrm{T}}{AUC_\textrm{R}\times CL_\textrm{R}}=\frac{AUC_\textrm{T}}{AUC_\textrm{R}}$$

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