Reanalysis for PK Reason: Gone with the Wind [Bioanalytics]

posted by Obinoscopy  – USA, 2020-07-20 16:12 (1806 d 20:55 ago) – Posting: # 21761
Views: 10,657

Hi Dshah

time concentration 1 concentration 2 concentration 3 concentration 4

❝ AUC      826.125         826.375         826.625         826.75


❝ I believe that such small change in AUC can be considered non-significant. :-)


I agree with you that these changes are very little. But you'd be amazed at how the difference between 826.125 and 826.375 is enough to make a study that failed (eg CI of T/R: 79.99 - 111.11) to pass (eg CI of T/R: 80.02 - 111.11).

Regards,

Scopy

Complete thread:

UA Flag
Activity
 Admin contact
23,425 posts in 4,928 threads, 1,680 registered users;
64 visitors (0 registered, 64 guests [including 39 identified bots]).
Forum time: 13:07 CEST (Europe/Vienna)

Fools with Tools Are Still Fools!    Anonymous

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5