3-period full replicates [Design Issues]

posted by Helmut Homepage – Vienna, Austria, 2020-07-20 12:04 (1454 d 15:41 ago) – Posting: # 21757
Views: 2,260

Hi Loky do,

❝ I think some countries like ours are very traditional in following guidelines,…


Agree. But the Egyptian GL of 2017 in Section 3.2 recommends the EMA’s approach and not the FDA’s. That’s not a different league but a different sport. For the SAS-codes recommended by the EMA see the Q&A document. Alternatively* you can use Phoenix/WinNonlin, STATISTICA, SPSS, Stata, JPM, or the [image]-pack­age replicateBE.

❝ why using partially replicate design is not favorable nowadays? :confused:


As a starter see this post and that one. I suggest also to search the forum with the keywords lousy and design. Most important reasons:

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