Sequence assignments in partially replicate design [Design Issues]

posted by Loky do – Egypt, 2020-07-19 01:33 (275 d 20:24 ago) – Posting: # 21746
Views: 1,169

Dears

In partially replicate 3-way design, FDA recommends using the following example for sequence assignments 1,2,3 --> (TRR, RTR, RRT), if we used different sequence assignments 1,2,3 --> (TRR, RRT, RTR), is this change significant? or is it ok as long as it's considered in statistical analysis?

Thanks in advance

Complete thread:

Activity
 Admin contact
21,419 posts in 4,475 threads, 1,510 registered users;
online 14 (0 registered, 14 guests [including 7 identified bots]).
Forum time: Tuesday 21:58 CEST (Europe/Vienna)

We have to remember that what we observe is not nature herself,
but nature exposed to our method of questioning.    Werner Heisenberg

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5