Sequence assignments in partially replicate design [Design Issues]

posted by Loky do – Egypt, 2020-07-19 01:33 (431 d 03:14 ago) – Posting: # 21746
Views: 1,469

Dears

In partially replicate 3-way design, FDA recommends using the following example for sequence assignments 1,2,3 --> (TRR, RTR, RRT), if we used different sequence assignments 1,2,3 --> (TRR, RRT, RTR), is this change significant? or is it ok as long as it's considered in statistical analysis?

Thanks in advance

Complete thread:

Activity
 Admin contact
21,691 posts in 4,534 threads, 1,541 registered users;
online 3 (0 registered, 3 guests [including 2 identified bots]).
Forum time: Thursday 04:48 CEST (Europe/Vienna)

Learning is a lifetime process, but there comes a time
when we must stop adding and start updating.    Robert Brault

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5